Exciting news! As mentioned above, picocli offers tooling to make it easy to create GraalVM native images for picocli-based command line applications. I would like to learn more to see how picocli can be improved to also make it easy for people to write Scala Native command line applications with it.
Is there a link about requirements for libraries that facilitates their use in Scala Native? Looking at the reflective instantiation support in the OP, it appears that classes need to be annoted with @EnableReflectiveInstantiation before they can be reflectively instantiated in a Scala Native app.
Picocli uses reflection internally to instantiate subcommands and other components. Some of these may be written in Scala and can be annotated with @EnableReflectiveInstantiation, but some of them (like a number of picocli built-in components) are written in Java and do not have this annotation.
So, I hope there will be another mechanism separate from this annotation to register classes that need to be instantiated reflectively. If these requirements are documented somewhere, library authors can prepare to make it possible for their libraries to be used in Scala Native.